There's evidence that a new breakthrough in preventing HIV infections may be on the horizon. The work is not yet published, but will be presented at a global AIDS conference in France in a month. I'm curious to see how their study was run, specifically, and how they designed the vaccine.
Also, I wonder if an AIDS vaccine would need to be similar to the vaccine for influenza. Because both evolve so rapidly, must they continue to re-design the vaccine to keep up with the virus' wily evolutionary rate?